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Bioconjugate Techniques

Copertina anteriore
4 Recensioni
Academic Press, 26/lug/2010 - 1323 pagine
Bioconjugate Techniques, 2e provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

*A one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab, allowing for fast retrieval of tried and tested techniques for synthesizing bioconjugates.

*Step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates.

*Includes more than 600 figures that visually describe the complex reactions associated with the synthesis of bioconjugates, giving researchers a better understanding of how the commercially available reagents facilitate the crosslinking of peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

*Includes entirely new chapters on the latest areas in the field of bioconjugation as follows:
Microparticles and nanoparticles
Silane coupling agents
Dendrimers and dendrons
Chemoselective ligation
Quantum dots
Lanthanide chelates
Cyanine dyes
Discrete PEG compounds
Buckyballs, fullerenes, and carbon nanotubes
Mass tags and isotope tags
Bioconjugation in the study of protein interactions
  

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Review: Bioconjugate Techniques

Recensione dell'utente  - Rafe - Goodreads

A fabulously useful book for the chemical biologist. Presents straightforward coupling and labeling strategies with detailed protocols. Leggi recensione completa

Libri correlati

Indice

Bioconjugate Reagents
213
Bioconjugate Applications
743
References
1041

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Pagina 1085 - Langer, PR, Waldrop, AA, and Ward, DC (1981) Enzymatic synthesis of biotinlabeled polynucleotides: novel nucleic acid affinity probes.
Pagina 1074 - I. (1968) Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J. Biol. Chem. 243, 3553-3555.
Pagina 1077 - Jaiswal JK, Mattoussi H, Mauro JM, Simon SM. Long-term multiple color imaging of live cells using quantum dot bioconjugates.
Pagina 1051 - Butler, JE, Ni, L., Nessler, R., Joshi, KS, Suter, M., Rosenberg, B., Chang, J., Brown, WR, and Cantarero, LA (1992) The physical and functional behavior of capture antibodies adsorbed on polystyrene.
Pagina 1062 - Fields, S. and Song, O. (1989) A novel genetic system to detect protein-protein interactions. Nature 340, 245-246.
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