Introduction to MicrofluidicsOUP Oxford, 25 nov 2005 - 310 pagine Microfluidics deals with fluids flowing in miniaturized systems. It is a young discipline, which is expected to substantially expand over the next few years, stimulated by the considerable development of applications in the pharmaceutical, biomedical and chemical engineering domains. The book is an introduction to this discipline. In the first chapter, it presents a short historical background and discusses the main perspectives of the domain, at economical and scientific levels. Then the physics of miniaturization and the fluid mechanics of microflows are discussed. In the following three chapters, dispersion, electrical and thermal phenomena in miniaturized devices are presented. A brief introduction to microfabrication techniques is given in chapter six and the book concludes by providing a few examples of microfluidic systems. The book is written in a simple, direct, pedagogical way. It emphasizes concepts and understanding, rather than technical detail. It offers a cross-disciplinary view of the field embracing biological, chemical, physical and engineering perspectives. By using the book, the reader will have concepts, methods and data to grasp situations which typically arise in microfluidic systems. |
Sommario
1 | |
Physics at the micrometric scale | 24 |
Hydrodynamics of microfluidic systems | 70 |
Diffusion mixing and separation in microsystems | 130 |
The electrohydrodynamics of microsystems | 189 |
Microfluidics and thermal transfers | 216 |
An introduction to microfabrication | 244 |
Some microfluidic devices | 282 |
Conclusion | 296 |
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adsorption analysis boundary conditions boundary layer calculation canal capillary capillary electrophoresis chaotic chapter charge chemical chemical kinetics chromatography concentration consider constant cross-section defined density deposition devices displacement domain droplets effect electric field Electro-osmosis electrodes electrophoresis electrostatic emulsions energy equation equilibrium etching evaporation example expression fabrication Figure flow fluid flux forces function glass gradient heat hydrodynamic interface ions kinetics Knudsen number lab-on-a-chip large number length liquid mean free path MEMS microcanal microexchanger microfabrication microfluidic systems microfluidics micrometers microreactors microsystems miniaturized systems mixing mold molecules nanometers Navier-Stokes equation obtain order of magnitude particles PDMS Peclet Peclet number phenomena photolithography Phys physical possible pressure problem pump quantity reactants reaction regime relation resist Reynolds numbers scaling laws separation shown in Fig silicon situation solution solvent structure substrate surface surfactant technique temperature tetradecane theoretical plates thermal thickness values valves velocity viscosity wafer width
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