Drug and Tracer Kinetics

a₁ absorption according amount analog analysis applied arms b₁ b₂ becomes behavior biological systems blood calculation called closed coefficients compartment systems complex computers concentration connected considered constant corresponds curve derivative described determine differential distribution drug elimination equal Equation example exit experimental exponential Figure flow formed fractional function G(t given glucose hence indicate injected interest introduced irreversible k₁ k₂ kinetics known labeled Laplace transforms linear mammillary material means measure ments method multiplying node obtain organism path plasma poles possible precursor present problem processes reactions recycling represents respect scheme solution specific activity steady steady-state straight line substance suppose system with three Table term three compartments tissues tracer transfer constants transfer function turnover rate various volume weighting function X₁ zero Хо