Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer

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John Wiley & Sons, 18 mag 2012 - 438 pagine
The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
 

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Indice

18
3
Cancer Models
31
The Warburg Dispute
107
Is Respiration Normal in Cancer Cells?
119
Is Mitochondrial Glutamine Fermentation a Missing Link in
133
Respiratory Insufficiency the Retrograde Response and the Origin
177
The Ultimate Tumor Suppressor
195
Abnormalities in Growth Control Telomerase Activity Apoptosis
207
Nothing in Cancer Biology Makes Sense Except in the Light
261
Cancer Treatment Strategies
277
Metabolic Management of Cancer
291
Patient Implementation of Metabolic Therapies for Cancer
355
Cancer Prevention
375
Case Studies and Personal Experiences in Using the Ketogenic Diet
387
ZupecKania
400
Index
409

Metastasis
215
Mitochondrial Respiratory Dysfunction and the Extrachromosomal
253

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Informazioni sull'autore (2012)

THOMAS N. SEYFRIED, PhD, has taught and conducted research in the fields of neurogenetics, neurochemistry, and cancer for more than twenty-five years at Yale University and Boston College. He has published more than 150 scientific articles and book chapters and is on the editorial boards of Nutrition & Metabolism, Journal of Lipid Research, Neurochemical Research, and ASN Neuro.

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