Mammalian DevelopmentPeter Lonai CRC Press, 1 set 1996 - 387 pagine A collection of essays on the developmental biology of mammals. The classical approach to embryology, combined with the powerful recombinant DNA technologies, have created in developmental biology one of the most active areas of biological research. It not only aids understanding of how the body and the brain are formed, but also furthers knowledge in fields with direct clinical importance such as gene regulation, cancer, regeneration, wound healing, bone, kidney and muscle development. |
Sommario
The Role of Brachyury in the Axial Development and Evolution | 29 |
Homeobox Genes in the Developing Vertebrate Brain | 55 |
In vitro and in vivo Approaches to the Molecular Analysis of Mouse | 101 |
Molecular Control of Growth and Pattern Formation in | 135 |
A Genetic Perspective | 151 |
A Model System for Brain | 173 |
Control of Floor Plate Identity and Function in the Embryonic | 199 |
Functional Analysis of the FGF System | 217 |
The Family of VEGF Tyrosine Kinase Receptors | 233 |
Targeted Expression of Dominantnegative FGF Receptors in Transgenic | 249 |
Insights from Human Diseases WT1 and PAX6 as Paradigms | 269 |
Biochemical and Cellular Aspects of Wound Repair | 293 |
Screens for Developmentally Regulated | 321 |
Engineering the Mouse Genome | 339 |
Modulation of Gene Activity in the Mouse Mediated by CRE | 373 |
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Acad activity allele analysis axis axons binding Biol cell lines chick chromosome cloned Cre recombinase defects deletion developmental differentiation distal domain dominant-negative dorsal Drosophila early ectoderm ectopic embryo endoderm endogenous endothelial cells epiblast epidermis expression pattern F-spondin fate fetal FGF receptor fibroblast growth factor Figure floor plate FLT4 function gastrulation gene expression genetic genome germ layers hematopoietic hindbrain homeobox homozygous induced interactions isoforms keratinocytes lacZ layer ligand limb bud lineage loxP mammalian mesenchyme mesoderm midbrain molecular molecules morphogenetic mouse embryo mRNA muscle mutant mice mutations MyoD myogenic myogenin Natl neural tube neurons normal notochord Oncogene Otx2 PDGF phenotype precursors primitive streak Proc promoter protein Puelles recombinase region regulation reporter gene role segmentation selectable marker sequence signal skeletal somite specific splicing suggest targeted tissue transcription factor transgenic transgenic mice tumor tyrosine kinase vector VEGF ventral vertebrate vitro vivo Wilms wound healing Xenopus zebrafish