Experimental Investigation of the Pulmonary Toxicity of Polyvinyl Chloride Particles
Leuven University Press, 2003 - 156 pagine
"This is a Ph.D. dissertation. Historically, occupational interstitial lung disease was common in workers who had inhaled mineral dusts such as silica, asbestos, and coal. With improved industrial hygiene and reduced mining and use of these agents, heavy e"
Cosa dicono le persone - Scrivi una recensione
Nessuna recensione trovata nei soliti posti.
In vitro toxicity assessment of polyvinyl chloride particles and comparison
Role of residual additives in the cytotoxicity and cytokine release caused
Pulmonary toxicity of polyvinyl chloride particles after a single
Pulmonary toxicity of polyvinyl chloride particles after repeated
Effect of prior bronchoalveolar lavage and fixation method on lung
Effect of PVCS4 particles
50 mg/kg BW 90 days A549 cell line alveolar macrophages alveoli animals APME assay assessed BALF bronchoalveolar lavage CD4/CD8 ratio cell cultures Cell viability Concentration mg/ml cytokine cytokine release cytotoxicity Days after instillation E3 and E8 EC50 values emulsion PVC particles eosinophils epithelial ethanol experimental fibrosis h-AM h-RBC h-TII Health hemolysis hemolysis test histopathology Hoet human incubation induced inflammation inhalation interleukin-8 interstitial lung disease lactate dehydrogenase lung weight lymphocytes macrophages Min-U-Sil MTT assay Nemery neutrophils occupational exposure panel pneumoconiosis pneumocytes polyvinyl chloride polyvinyl chloride dust polyvinyl chloride particles present study pulmonary toxicity PVC dust PVC-E PVC-E3 and PVC-W3 PVC-W3 particles r-AM r-TII residual additives Respir response samples significant silica single instillation single intratracheal instillation sodium supernatant Thorax THP-1 cells tissue TNF-o Toxicol Toxicology type II pneumocytes vehicle control vinyl chloride vitro vitro cytotoxicity vitro studies vitro toxicity vivo washed workers