Alternatives to Laboratory Animals: ATLA., Volume 36,Edizioni 1-3FRAME, 2008 |
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acute toxicity allergens alternative methods analysis animal testing animal welfare applied ATLA Basketter benzoic acid cell culture cell line clotrimazole compounds concentration corneal cytotoxicity digoxin donor Draize Draize test ecotoxicity ECVAM effects embryo endocrine disruptors endpoints EpiDerm EPISKIN ESAC European evaluation EVEIT experimental experiments exposure eye irritation test Figure flufenamic acid fly ash Germany hapten human ICCVAM Igepal INVITTOX irritation potential Ispra ivermectin Journal laboratory animals LLNA lymph node mannitol measured membrane ment metabolism microsurgical non-irritant nucleophile number of animals OECD OECD TG peptide performed permeability permeation pig skin potency prediction protein QSAR REACH system reactivity receptor regulatory repeat dose reproductive toxicity risk assessment samples scientific silico skin sensitisation statistics stem cells test methods test substance testing strategies testosterone tion tissue toxicity toxicity testing Toxicology in Vitro toxin validation study values viability vitro tests workshop zebrafish zebrafish embryo