Obesity, Towards a Molecular Approach: Proceedings of a UCLA Symposium Held at Keystone, Colorado, April 17-23, 1989

abdominal action activity adipocytes afferent alterations animals associated balance binding Biochem body weight brain brown adipose tissue central changes Clin cold component concentrations culture decrease demonstrated diabetes diet dietary differentiation dopamine eating effect energy enzyme evidence expression factor fat cells fatty acid feeding Figure food intake function gene genetic glucose human hypothalamus hypothyroid important increased indicate induced influence infusion inhibit insulin receptor insulin resistance Invest involved levels lipase lipid lipolysis liver mass measured mechanisms membrane metabolism molecular mouse mRNA muscle nervous system normal nuclear nutrient obesity observed pathway patients Physiol plasma possible produced protein rats recently receptors reduced region regulation release response role sensitive sequence serotonin shown shows signals specific stimulation studies subjects suggest sympathetic sympathetic activity sympathetic nervous synthesis Table thermogenesis thyroid hormone transcription transport various vitro vivo Young