PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 82
Pagina 160
... Chapter 19 Table 8.3 Summary of drugs that affect noradrenergic transmission Type Tachycardia , dysrhythmias , tremor , peripheral ... Chapter 15 See Chapter 35 See Chapter 38 Sympathomimetic Tyramine ( indirectly 160 CHEMICAL MEDIATORS.
... Chapter 19 Table 8.3 Summary of drugs that affect noradrenergic transmission Type Tachycardia , dysrhythmias , tremor , peripheral ... Chapter 15 See Chapter 35 See Chapter 38 Sympathomimetic Tyramine ( indirectly 160 CHEMICAL MEDIATORS.
Pagina 161
... Chapter 35 See Chapter 38 Sympathomimetic Tyramine ( indirectly acting ) NA release Amphetamine NA release , MAO inhibitor , uptake 1 inhibitor , CNS stimulant Ephedrine NA release , CNS stimulant B - agonist , weak No clinical uses ...
... Chapter 35 See Chapter 38 Sympathomimetic Tyramine ( indirectly acting ) NA release Amphetamine NA release , MAO inhibitor , uptake 1 inhibitor , CNS stimulant Ephedrine NA release , CNS stimulant B - agonist , weak No clinical uses ...
Pagina 483
... chapters owe their effects to mechanisms that are related to these mediators . They differ from the amino acid transmitters discussed in Chapter 29 in being more localised in parti- cular neurons and tracts , and they are broadly ...
... chapters owe their effects to mechanisms that are related to these mediators . They differ from the amino acid transmitters discussed in Chapter 29 in being more localised in parti- cular neurons and tracts , and they are broadly ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular