PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 95
Pagina 110
... acetylcholine 110 Acetylcholine receptors 112 Nicotinic receptors 112 Muscarinic receptors 113 Physiology of cholinergic transmission 113 Acetylcholine synthesis and release 114 Electrical events in transmission at cholinergic synapses ...
... acetylcholine 110 Acetylcholine receptors 112 Nicotinic receptors 112 Muscarinic receptors 113 Physiology of cholinergic transmission 113 Acetylcholine synthesis and release 114 Electrical events in transmission at cholinergic synapses ...
Pagina 114
... ACETYLCHOLINE SYNTHESIS AND RELEASE Acetylcholine metabolism is well reviewed by Parsons et al . ( 1993 ) . Acetylcholine is synthesised within the nerve terminal from choline , which is taken up into the nerve terminal by an active ...
... ACETYLCHOLINE SYNTHESIS AND RELEASE Acetylcholine metabolism is well reviewed by Parsons et al . ( 1993 ) . Acetylcholine is synthesised within the nerve terminal from choline , which is taken up into the nerve terminal by an active ...
Pagina 115
... acetylcholine actively , by means of a specific transport protein , a serpentine structure comprising 12 transmembrane helical regions , belonging to the general family of amine transporters which are responsible for transmitter ...
... acetylcholine actively , by means of a specific transport protein , a serpentine structure comprising 12 transmembrane helical regions , belonging to the general family of amine transporters which are responsible for transmitter ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
46 sezioni non visualizzate
Altre edizioni - Visualizza tutto
Parole e frasi comuni
acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular