PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
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Pagina 518
... agents ; it is pronounced with ether and nitrous oxide , but not with halothane . • Stage II - Excitement . The subject loses conscious- ness , and no longer responds to non - painful stimuli , but responds in a reflex fashion to ...
... agents ; it is pronounced with ether and nitrous oxide , but not with halothane . • Stage II - Excitement . The subject loses conscious- ness , and no longer responds to non - painful stimuli , but responds in a reflex fashion to ...
Pagina 681
... agents , i.e. acting at all stages of the cell cycle and not having much effect on cells out of cycle : alkylating agents , dactinomycin , doxorubicin and cisplatin . • Cycle non - specific agents , i.e. acting on cells whether in cycle ...
... agents , i.e. acting at all stages of the cell cycle and not having much effect on cells out of cycle : alkylating agents , dactinomycin , doxorubicin and cisplatin . • Cycle non - specific agents , i.e. acting on cells whether in cycle ...
Pagina 795
... agents , 69 , 382 morphine - like drugs as , 382 , 595 Antimuscarinics , see Muscarinic ACh receptor antagonists Antimycobacterial drugs , see Antileprosy drugs ; Antituberculosis drugs Antimycotic agents , see Antifungal drugs Anti ...
... agents , 69 , 382 morphine - like drugs as , 382 , 595 Antimuscarinics , see Muscarinic ACh receptor antagonists Antimycobacterial drugs , see Antileprosy drugs ; Antituberculosis drugs Antimycotic agents , see Antifungal drugs Anti ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular