PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 80
Pagina 233
... decrease in prostanoid synthesis . An anti - inflammatory action : the decrease in vasodilator prostaglandins ( PGE2 , PGI2 ) means less vasodilatation and , indirectly , less oedema . Accumulation of inflammatory cells is not reduced ...
... decrease in prostanoid synthesis . An anti - inflammatory action : the decrease in vasodilator prostaglandins ( PGE2 , PGI2 ) means less vasodilatation and , indirectly , less oedema . Accumulation of inflammatory cells is not reduced ...
Pagina 421
... decreased production and action of cytokines including many interleukins , TNF , GM - CSF - reduced generation of eicosanoids - decreased generation of IgG - decrease in complement components in the blood . Overall effects : reduction ...
... decreased production and action of cytokines including many interleukins , TNF , GM - CSF - reduced generation of eicosanoids - decreased generation of IgG - decrease in complement components in the blood . Overall effects : reduction ...
Pagina 425
... decrease in extracellular fluid volume . There is a con- comitant decrease in the excretion of potassium ions resulting in hyperkalaemia , and also a moderate decrease in plasma bicarbonate . Regulation of aldosterone synthesis and ...
... decrease in extracellular fluid volume . There is a con- comitant decrease in the excretion of potassium ions resulting in hyperkalaemia , and also a moderate decrease in plasma bicarbonate . Regulation of aldosterone synthesis and ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
46 sezioni non visualizzate
Altre edizioni - Visualizza tutto
Parole e frasi comuni
acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular