PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
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Pagina 614
... dependence 614 Reward pathways 616 Habituation mechanisms 617 Genetic factors 617 Pharmacological approaches to treating drug dependence 618 Nicotine and tobacco 618 Pharmacological ... dependence and drug abuse The nature of drug dependence.
... dependence 614 Reward pathways 616 Habituation mechanisms 617 Genetic factors 617 Pharmacological approaches to treating drug dependence 618 Nicotine and tobacco 618 Pharmacological ... dependence and drug abuse The nature of drug dependence.
Pagina 615
... Dependence liability Discussed in Ch . 37 Diamorphine V. strong Ch . 37 Ethanol Strong This chapter Barbiturates ... dependence ( see below ) . Drug abuse and substance abuse are more general terms , meaning any use of illicit substances ...
... Dependence liability Discussed in Ch . 37 Diamorphine V. strong Ch . 37 Ethanol Strong This chapter Barbiturates ... dependence ( see below ) . Drug abuse and substance abuse are more general terms , meaning any use of illicit substances ...
Pagina 616
... dependence . ABSTINENCE SYNDROME Delayed Long - lasting ( days ) • Increases with repetition Drug dependence Dependence is defined as an excessive craving which develops as a result of repeated administration of the drug . Dependence ...
... dependence . ABSTINENCE SYNDROME Delayed Long - lasting ( days ) • Increases with repetition Drug dependence Dependence is defined as an excessive craving which develops as a result of repeated administration of the drug . Dependence ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular