PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
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Pagina 410
... Hormone affected in anteror pituitary ( and related drugs ) Corticotrophin ( ACTH ; tetracosactrin ) Growth hormone ( GH ; somatotropin , somatropin , somatrem ) Follicle - stmulating hormone ( FSH ) . See Chapter 26 Luteinising hormone ...
... Hormone affected in anteror pituitary ( and related drugs ) Corticotrophin ( ACTH ; tetracosactrin ) Growth hormone ( GH ; somatotropin , somatropin , somatrem ) Follicle - stmulating hormone ( FSH ) . See Chapter 26 Luteinising hormone ...
Pagina 412
... HORMONE ( GnRH ) Gonadotrophin - releasing hormone is a decapeptide which releases both follicle - stimulating hormone and lutein- ising hormone . It is also available as a preparation called gonadorelin . Its actions and uses are ...
... HORMONE ( GnRH ) Gonadotrophin - releasing hormone is a decapeptide which releases both follicle - stimulating hormone and lutein- ising hormone . It is also available as a preparation called gonadorelin . Its actions and uses are ...
Pagina 679
... hormone - dependency of tumours treated with steroids is , in general , related to the presence of steroid receptors in the malignant cells . Gonadotrophin - releasing hormone analogues As explained in Chapter 26 ( p . 446 ) analogues ...
... hormone - dependency of tumours treated with steroids is , in general , related to the presence of steroid receptors in the malignant cells . Gonadotrophin - releasing hormone analogues As explained in Chapter 26 ( p . 446 ) analogues ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular