PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
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Pagina 305
... INHIBITORS ( STATINS ) The rate - limiting enzyme in cholesterol synthesis is HMG - CoA reductase which catalyses the conversion of HMG - CoA * to mevalonic acid ( MVA ) ( see Fig . 16.1 ) . Several fungal metabolites are potent inhibitors ...
... INHIBITORS ( STATINS ) The rate - limiting enzyme in cholesterol synthesis is HMG - CoA reductase which catalyses the conversion of HMG - CoA * to mevalonic acid ( MVA ) ( see Fig . 16.1 ) . Several fungal metabolites are potent inhibitors ...
Pagina 560
... inhibitors Clorgyline Selegiline Moclobemide CH3 Non - specific inhibitors Pargyline Clorgyline OCH2CH2CH2NCH2C = CH Tranylcypromine Iproniazid CH3 Selegiline CH , CHNCH , C = CH CH3 activity , whose members showed mental retardation ...
... inhibitors Clorgyline Selegiline Moclobemide CH3 Non - specific inhibitors Pargyline Clorgyline OCH2CH2CH2NCH2C = CH Tranylcypromine Iproniazid CH3 Selegiline CH , CHNCH , C = CH CH3 activity , whose members showed mental retardation ...
Pagina 717
... Inhibition of penetration of host cell ○ Amantadine inhibits uncoating and is effective against influenza A virus . • Gamma globulin ' neutralises ' viruses . Inhibition of transcription of the viral genome DNA polymerase inhibitors ...
... Inhibition of penetration of host cell ○ Amantadine inhibits uncoating and is effective against influenza A virus . • Gamma globulin ' neutralises ' viruses . Inhibition of transcription of the viral genome DNA polymerase inhibitors ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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