PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 86
Pagina 110
... muscarinic receptors 118 Muscarinic agonists 118 Muscarinic antagonists 119 Drugs affecting autonomic ganglia 123 Ganglion stimulants 123 Ganglion - blocking drugs 123 Neuromuscular - blocking drugs 125 Non - depolarising blocking ...
... muscarinic receptors 118 Muscarinic agonists 118 Muscarinic antagonists 119 Drugs affecting autonomic ganglia 123 Ganglion stimulants 123 Ganglion - blocking drugs 123 Neuromuscular - blocking drugs 125 Non - depolarising blocking ...
Pagina 118
... muscarinic agonists ⚫ muscarinic antagonists ⚫ ganglion - stimulating drugs • ganglion - blocking drugs • neuromuscular - blocking drugs ⚫ anticholinesterases and other drugs that enhance cholinergic transmission . DRUGS AFFECTING ...
... muscarinic agonists ⚫ muscarinic antagonists ⚫ ganglion - stimulating drugs • ganglion - blocking drugs • neuromuscular - blocking drugs ⚫ anticholinesterases and other drugs that enhance cholinergic transmission . DRUGS AFFECTING ...
Pagina 241
... muscarinic - receptor antagonism . Used in motion sickness Some local anaesthetic action and fairly marked muscarinic - receptor antagonism . Weak a1 - adrenoceptor antagonism . Anti - emetic . Injection can be painful Potent H1 ...
... muscarinic - receptor antagonism . Used in motion sickness Some local anaesthetic action and fairly marked muscarinic - receptor antagonism . Weak a1 - adrenoceptor antagonism . Anti - emetic . Injection can be painful Potent H1 ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular