PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
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Pagina 409
H. P. Rang, M. Maureen Dale, James Ritter. The pituitary and adrenal cortex Table 24.1 Hormones secreted by the hypothalamus and the anterior. The pituitary 409 Anterior pituitary ( adenohypophysis ) 409 Hypothalamic hormones 410 -Growth ...
H. P. Rang, M. Maureen Dale, James Ritter. The pituitary and adrenal cortex Table 24.1 Hormones secreted by the hypothalamus and the anterior. The pituitary 409 Anterior pituitary ( adenohypophysis ) 409 Hypothalamic hormones 410 -Growth ...
Pagina 411
... PITUITARY Secondary- ( neurohypophysis ) capillary plexus Anterior pituitary Venous outflow Somatropin Venous outflow Growth Artery hormone ANTERIOR PITUITARY Fig . 24.1 Schematic diagram of vascular and neuronal relationships between ...
... PITUITARY Secondary- ( neurohypophysis ) capillary plexus Anterior pituitary Venous outflow Somatropin Venous outflow Growth Artery hormone ANTERIOR PITUITARY Fig . 24.1 Schematic diagram of vascular and neuronal relationships between ...
Pagina 412
... pituitary to secrete corticotrophin ; to assess whether a deficiency of corticotrophin is due to a pituitary or a hypothalamic defect ; and to evaluate hypo- thalamic pituitary function after therapy for Cushing's syndrome ( see Fig ...
... pituitary to secrete corticotrophin ; to assess whether a deficiency of corticotrophin is due to a pituitary or a hypothalamic defect ; and to evaluate hypo- thalamic pituitary function after therapy for Cushing's syndrome ( see Fig ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular