PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 82
Pagina 301
... risk factors for atherosclerosis 301 The relationship between atherosclerosis / thrombosis and LDL - cholesterol concentration in the plasma 302 Lipoprotein transport in the blood 302 Classification of hyperlipoproteinaemias 304 Lipid ...
... risk factors for atherosclerosis 301 The relationship between atherosclerosis / thrombosis and LDL - cholesterol concentration in the plasma 302 Lipoprotein transport in the blood 302 Classification of hyperlipoproteinaemias 304 Lipid ...
Pagina 443
... risk of coronary heart disease ( the commonest cause of death in postmenopausal women ) ; epidemiological studies suggest that there is a 50 % reduction . Recent evidence indicates that addition of progestogens to the HRT regime ...
... risk of coronary heart disease ( the commonest cause of death in postmenopausal women ) ; epidemiological studies suggest that there is a 50 % reduction . Recent evidence indicates that addition of progestogens to the HRT regime ...
Pagina 448
... risk of cardiovascular disease ( venous thromboembolism , myocardial infarction , stroke ) ? With second - generation pills ( oestrogen con- tent less than 50 μg ) , the risk of thromboembolism is small and is confined to specific ...
... risk of cardiovascular disease ( venous thromboembolism , myocardial infarction , stroke ) ? With second - generation pills ( oestrogen con- tent less than 50 μg ) , the risk of thromboembolism is small and is confined to specific ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular