PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
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Pagina 436
... steroids 445 Anti - androgens 445 Gonadotrophin - releasing hormone : agonists and antagonists 446 -Danazol 447 Gonadotrophins and analogues 447 Drugs used for contraception 447 Oral contraceptives 447 Other drug regimes used for ...
... steroids 445 Anti - androgens 445 Gonadotrophin - releasing hormone : agonists and antagonists 446 -Danazol 447 Gonadotrophins and analogues 447 Drugs used for contraception 447 Oral contraceptives 447 Other drug regimes used for ...
Pagina 438
... steroids affect sexual behaviour . Two types of control are recognised , namely organisational and activational . The former refers to the fact that sexual differentiation of the brain can be permanently altered by the presence or ...
... steroids affect sexual behaviour . Two types of control are recognised , namely organisational and activational . The former refers to the fact that sexual differentiation of the brain can be permanently altered by the presence or ...
Pagina 445
... steroids ( see p . 421 ) . Preparations Testosterone itself can be given by subcutaneous im- plantation . Testosterone enanthate and testosterone proprionate are given by intramuscular depot injection . Testosterone undecanoate and ...
... steroids ( see p . 421 ) . Preparations Testosterone itself can be given by subcutaneous im- plantation . Testosterone enanthate and testosterone proprionate are given by intramuscular depot injection . Testosterone undecanoate and ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular