PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
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Pagina 97
... sympathetic ganglia are found only in head and neck . The sympathetic preganglionic neurons have their cell bodies in the lateral horn of the grey matter of the thoracic and lumbar segments of the spinal cord , and the fibres leave the ...
... sympathetic ganglia are found only in head and neck . The sympathetic preganglionic neurons have their cell bodies in the lateral horn of the grey matter of the thoracic and lumbar segments of the spinal cord , and the fibres leave the ...
Pagina 98
... sympathetic / parasympathetic classification . Incoming nerves from both the sympathetic and the parasympathetic systems terminate on enteric neurons , as well as running directly to smooth muscle , glands and blood vessels . Some ...
... sympathetic / parasympathetic classification . Incoming nerves from both the sympathetic and the parasympathetic systems terminate on enteric neurons , as well as running directly to smooth muscle , glands and blood vessels . Some ...
Pagina 105
... sympathetic neurons ( e.g. blood vessels , Postganglionic sympathetic neurons ( e.g. blood vessels ) NANC innervation of airways smooth muscle Sympathetic ganglia NOS. Transmitter Location Function Non - peptides ATP GABA , 5 - HT ...
... sympathetic neurons ( e.g. blood vessels , Postganglionic sympathetic neurons ( e.g. blood vessels ) NANC innervation of airways smooth muscle Sympathetic ganglia NOS. Transmitter Location Function Non - peptides ATP GABA , 5 - HT ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular