PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 88
Pagina 105
... Transmitter Location Function Non - peptides ATP GABA , 5 - HT Dopamine NO NO Peptides vas deferens ) Enteric ... transmitter with ACh Bronchodilatation Slow depolarisation Co - transmitter with ACh Slow depolarisation Co - transmitter ...
... Transmitter Location Function Non - peptides ATP GABA , 5 - HT Dopamine NO NO Peptides vas deferens ) Enteric ... transmitter with ACh Bronchodilatation Slow depolarisation Co - transmitter with ACh Slow depolarisation Co - transmitter ...
Pagina 108
... transmitter . The simultaneous transport of ions along with the transmitter means that the process gene- rates a net current across the membrane , which can be measured directly , and used to monitor the transport process ( Brew ...
... transmitter . The simultaneous transport of ions along with the transmitter means that the process gene- rates a net current across the membrane , which can be measured directly , and used to monitor the transport process ( Brew ...
Pagina 470
... transmitter , glutamate , and the inhibitory transmitters , GABA and glycine . EXCITATORY AMINO ACIDS ( EAAs ) EAAS AS CNS TRANSMITTERS L - glutamate is the principal and ubiquitous excitatory transmitter in the central nervous system ...
... transmitter , glutamate , and the inhibitory transmitters , GABA and glycine . EXCITATORY AMINO ACIDS ( EAAs ) EAAS AS CNS TRANSMITTERS L - glutamate is the principal and ubiquitous excitatory transmitter in the central nervous system ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular