PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
Risultati 1-3 di 77
Pagina 265
... treat heart failure , and most of them decrease plasma [ K ] thereby increasing the risk of arrhythmia . Clinical aspects Clinical use and unwanted effects of digoxin are summarised on this page . Cardiac glycosides Act by inhibiting Na ...
... treat heart failure , and most of them decrease plasma [ K ] thereby increasing the risk of arrhythmia . Clinical aspects Clinical use and unwanted effects of digoxin are summarised on this page . Cardiac glycosides Act by inhibiting Na ...
Pagina 679
... treat advanced breast cancer in premenopausal women and prostate cancer . The surge of testosterone secretion which can occur in prostate cancer patients so treated can be prevented by an anti- androgen such as cyproterone ( p . 445 ) ...
... treat advanced breast cancer in premenopausal women and prostate cancer . The surge of testosterone secretion which can occur in prostate cancer patients so treated can be prevented by an anti- androgen such as cyproterone ( p . 445 ) ...
Pagina 714
... treat herpes simplex infections ( genital herpes , mucocutaneous herpes and herpes encephalitis ) ⚫ to treat varicella ( chickenpox ) in immunocompromised patients prophylactically in patients who are to be treated with ...
... treat herpes simplex infections ( genital herpes , mucocutaneous herpes and herpes encephalitis ) ⚫ to treat varicella ( chickenpox ) in immunocompromised patients prophylactically in patients who are to be treated with ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular