PharmacologyChurchill Livingstone, 1999 - 830 pagine The aim of this work is not only to describe what drugs do, but to emphasize the mechanisms by which they act - where possible at the cellular and molecular level. Therapeutic agents have a high rate of obsolescence and many new ones are introduced each year; an appreciation of the mechanisms of action of the class of drugs to which a new agent belongs provides a starting point for understanding and using intelligently. |
Dall'interno del libro
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Pagina 53
... treatment ( A ) with that of a control group receiving an existing ' standard ' treatment ( B ) . Treatment A might be a new drug or a new combi- nation of existing drugs , or any other kind of therapeutic intervention such as a ...
... treatment ( A ) with that of a control group receiving an existing ' standard ' treatment ( B ) . Treatment A might be a new drug or a new combi- nation of existing drugs , or any other kind of therapeutic intervention such as a ...
Pagina 434
... treatment of hypothyroidism , unless it is due to iodine deficiency ( which is treated with iodide ; see above ) , is to administer the thyroid hormones themselves - used as replacement therapy . Thyroxine and triiodothyronine ...
... treatment of hypothyroidism , unless it is due to iodine deficiency ( which is treated with iodide ; see above ) , is to administer the thyroid hormones themselves - used as replacement therapy . Thyroxine and triiodothyronine ...
Pagina 738
... treatment and prophylaxis with chloroquine . Lancet 341 : 96-100 Nosten F , ter Kuile F O et al . 1993 Cardiac effects of antimalarial treatment with halofantrine . Lancet 341 : 1054-1056 O'Brien C 1997 Beating the malaria parasite at ...
... treatment and prophylaxis with chloroquine . Lancet 341 : 96-100 Nosten F , ter Kuile F O et al . 1993 Cardiac effects of antimalarial treatment with halofantrine . Lancet 341 : 1054-1056 O'Brien C 1997 Beating the malaria parasite at ...
Sommario
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Absorption and distribution of drugs | 61 |
Copyright | |
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acetylcholine action potential activity agents agonists amino acids anaesthetics antagonists antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ calcium cancer cardiac cause cells chemical clinical compounds cytokines decrease depolarisation depression disease diuretics dopamine dose drugs enzyme ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous ion channels kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals nervous system neurons nicotine noradrenaline normal occurs oestrogens opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma plasma concentration platelet presynaptic produce prostaglandins protein reactions receptors reduced release renal response result role secretion side-effects smooth muscle sodium steroids stimulation sympathetic synaptic synthesis therapeutic therapy tissues toxicity transmission transmitter treatment tubule tumour types unwanted effects uptake vascular