Principles of Cloning

Copertina anteriore
Jose Cibelli, Robert Lanza, Keith H.S. Campbell, Michael D. West
Elsevier, 14 set 2002 - 531 pagine
Principles of Cloning is the first comprehensive book on animal cloning since the creation of Dolly. The contributing authors are the principal investigators on each of the animal species cloned to date, and are expertly qualified to present the state-of-the-art information in their respective areas. Editors Cibelli, Lanza and West garnered worldwide spotlight late in 2001 when their company, Advanced Cell Technology, announced the successful engineering of the world's first cloned human embryo. The trio was featured in the US News & World Report December 2001 cover story, "The First Human Clone." The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine.

Key Features* First and most comprehensive book on animal cloning* Chapters written by the world' expert in each area * From the early experiments in amphibia to the latest one in mammals, everything is included in this book and told by the researcher that did it and how they did it* Basic biological mechanisms on how cloning works and all their current and potential applications* Cloning applications on basic biology, agriculture, biotechnology and medicine are included* Editors are the pioneers in the field

Dall'interno del libro

Sommario

Basic Biological Processes
19
Methods
153
Cloning by Species
279
Currently Sought after Species
401
Nuclear Transfer in Primates
417
Applications
433
Ethical and Legal Affairs
475
Final Remarks
495
AUTHOR INDEX
503
SUBJECT INDEX
523
Copyright

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Pagina 79 - Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292, 110-113.
Pagina 148 - Specific association of human telomerase activity with immortal cells and cancer.
Pagina 146 - Doetschman, TC, Eistetter, H., Katz, M., Schmidt, W., and Kemler, R. (1985) The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium.
Pagina 146 - M., and Van Blerkom, J. (1997). Oocyte influences on early development: The regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol. Hum. Reprod.
Pagina 491 - Vescovi, AL (1999). Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo.
Pagina 77 - Wolffe, AP (1998). Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription.
Pagina 74 - Broach, JR (1993) Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev.
Pagina 107 - Friedrich, G., and Soriano, P. (1991). Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5, 1513-1523.
Pagina 74 - Brownell, JE, Zhou, J., Ranalli, T., Kobayashi, R., Edmondson, DG, Roth, SY, and Allis, CD (1996). Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84, 843-85 1 . Brunei, A., Sweeney, LB, Sturgill, J.
Pagina 172 - Enhanced rates of cleavage and development for sheep zygotes cultured to the blastocyst stage in vitro in the absence of serum and somatic cells. Amino acids, vitamins, and culturing embryos in groups stimulate development.

Informazioni sull'autore (2002)

Dr. Cibelli is Professor of Animal Biotechnology at Michigan State University. He heads the Cellular Reprogramming Laboratory in the Departments of Animal Science and Physiology since 2003. From 2010 to 2017 he was also the Scientific Director of LARCel, a laboratory of cellular reprogramming dedicated to generating human pluripotent cells under GMP conditions for preclinical studies in Andalucia, Spain. Dr. Cibelli is internationally recognized as one of the pioneers in the area of cellular reprogramming using oocyte-driven protocols. Dr. Cibelli together with his colleagues, were responsible for the generation of the world's first transgenic cloned calves, the first stem cells by nuclear transfer in bovine, the first embryonic stem cells by parthenogenesis in primates and the generation of the first cell line of iPSCs using oocyte factors alone. His work has been published un numerous scientific journals including Science, Nature Biotechnology, Nature Medicine, Nature Methods, PNAS, Cell Stem Cell and JAMA.

Robert Lanza is an American scientist and author whose research spans the range of natural science, from biology to theoretical physics. TIME magazine recognized him as one of the “100 Most Influential People in the World, and Prospect magazine named him one of the Top 50 “World Thinkers. He has hundreds of scientific publications and over 30 books, including definitive references in the fields of stem cells, tissue engineering, and regenerative medicine. He’s a former Fulbright Scholar and studied with polio-pioneer Jonas Salk and Nobel laureates Gerald Edelman (known for his work on the biological basis of consciousness) and Rodney Porter. He also worked closely (and co-authored papers in Science on self-awareness and symbolic communication) with noted Harvard psychologist BF Skinner. Dr. Lanza was part of the team that cloned the world’s first human embryo, the first endangered species, and published the first-ever reports of pluripotent stem cell use in humans.

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