Cell Lineage and Embryo PatterningInternational Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus. Key Features * A number of important concepts are discussed, including: * How polarity is established during oogenesis * How germ cell determinants become organized in the establishment of the germ cell lineage * Different strategies used by organisms to establish the germ cell lineage * Similarities and differences between the mechanisms used in embryonic patterning * The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated * The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system * The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification |
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Sommario
Patterning of the Embryo | 231 |
Mechanisms to Establish Polarity and Initiate Cell Fate Determination | 519 |
Index | 609 |
Parole e frasi comuni
A-P axis activity ascidian asymmetric binding blastocyst blastomeres cadherins Caenorhabditis elegans catenin Cell Biol chick cleavage cystoblast cytoplasmic determinants Development 124 differentiation domain dorsal Drosophila early ectoderm ectopic egg chamber embryo embryogenesis encodes endoderm epiblast follicle cells formation function fusome gastrulation gene expression Genes Dev Genet germ plasm germline germline cyst germline stem cell gonad induce inhibition initiation interactions involved Jeffery left-right limb bud lineage markers maternal mechanisms mediated meiotic Melton mesoderm microtubule migration mitochondrial molecular molecules morphogenesis mouse embryo mRNA muscle mutants myoplasm neural crest neural plate neural tube nodal notochord nuclear oocyte oogenesis patterning PGCs phenotype plakoglobin polar granules pole cells posterior pole proliferation protein receptor region regulation repression ring canals RNA localization role sequence signaling pathway somatic specification Spradling stage suggest tion tissue transcription factor translational vegetal pole ventral vertebrate Wnt signaling Xenopus oocytes zebrafish zygotic
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