Cell Lineage and Embryo PatterningInternational Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus. Key Features * A number of important concepts are discussed, including: * How polarity is established during oogenesis * How germ cell determinants become organized in the establishment of the germ cell lineage * Different strategies used by organisms to establish the germ cell lineage * Similarities and differences between the mechanisms used in embryonic patterning * The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated * The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system * The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification |
Dall'interno del libro
Risultati 1-5 di 5
Pagina 11
B-line blastomeres in the vegetal hemisphere. The myoplasm, a yellow
cytoplasmic region containing mitochondria, pigment granules, and associated
cytoskeletal elements (Jeffery and Meier, 1983), is localized in the vegetal
posterior region ...
B-line blastomeres in the vegetal hemisphere. The myoplasm, a yellow
cytoplasmic region containing mitochondria, pigment granules, and associated
cytoskeletal elements (Jeffery and Meier, 1983), is localized in the vegetal
posterior region ...
Pagina 14
As shown in Figure 3C, the third cleavage of the ascidian embryo is equatorial,
distributing the myoplasm to the B4.1 and B4.1 cells at the eight-cell stage.
However, if four-cell embryos are compressed in a plane perpendicular to the ...
As shown in Figure 3C, the third cleavage of the ascidian embryo is equatorial,
distributing the myoplasm to the B4.1 and B4.1 cells at the eight-cell stage.
However, if four-cell embryos are compressed in a plane perpendicular to the ...
Pagina 28
The myoplasm lacks pigmentation in Molgula species. Fortunately, however, the
NN18 monoclonal antibody, which reacts specifically with the myoplasmic
cytoskeletal protein p58 (Swalla et al., 1991), allows the myoplasm to be detected
in ...
The myoplasm lacks pigmentation in Molgula species. Fortunately, however, the
NN18 monoclonal antibody, which reacts specifically with the myoplasmic
cytoskeletal protein p58 (Swalla et al., 1991), allows the myoplasm to be detected
in ...
Pagina 43
The screen resulted in the isolation of posterior end mark (pem), a black fragment
-enriched mRNA that is localized in the myoplasm. In striking contrast to other
RNAs localized in the myoplasm (see above), pem mRNA is not eventually ...
The screen resulted in the isolation of posterior end mark (pem), a black fragment
-enriched mRNA that is localized in the myoplasm. In striking contrast to other
RNAs localized in the myoplasm (see above), pem mRNA is not eventually ...
Pagina 52
... Localized RNAs in Ascidian Eggs and Embryos RNA Species Localization
Putative Function PCNA Styela clava Ectoplasm DNA replication Hrsmad1/5
Halocynthia roretzi Ectoplasm Signal transduction YC Styela clava Myoplasm
Unknown; ...
... Localized RNAs in Ascidian Eggs and Embryos RNA Species Localization
Putative Function PCNA Styela clava Ectoplasm DNA replication Hrsmad1/5
Halocynthia roretzi Ectoplasm Signal transduction YC Styela clava Myoplasm
Unknown; ...
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Sommario
Patterning of the Embryo | 231 |
Mechanisms to Establish Polarity and Initiate Cell Fate Determination | 519 |
Index | 609 |
Parole e frasi comuni
A-P axis activity ascidian asymmetric binding blastocyst blastomeres cadherins Caenorhabditis elegans catenin Cell Biol chick cleavage cystoblast cytoplasmic determinants Development 124 differentiation domain dorsal Drosophila early ectoderm ectopic egg chamber embryo embryogenesis encodes endoderm epiblast follicle cells formation function fusome gastrulation gene expression Genes Dev Genet germ plasm germline germline cyst germline stem cell gonad induce inhibition initiation interactions involved Jeffery left-right limb bud lineage markers maternal mechanisms mediated meiotic Melton mesoderm microtubule migration mitochondrial molecular molecules morphogenesis mouse embryo mRNA muscle mutants myoplasm neural crest neural plate neural tube nodal notochord nuclear oocyte oogenesis patterning PGCs phenotype plakoglobin polar granules pole cells posterior pole proliferation protein receptor region regulation repression ring canals RNA localization role sequence signaling pathway somatic specification Spradling stage suggest tion tissue transcription factor translational vegetal pole ventral vertebrate Wnt signaling Xenopus oocytes zebrafish zygotic
Brani popolari
Pagina 479 - TM (1994). Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775.
Pagina 178 - De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, JS, Schroeter, EH, Schrijvers, V., Wolfe, MS, Ray, WJ, Goate, A., and Kopan, R.
Pagina 177 - J. (1987). glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 51, 589-599.
Pagina 479 - JLR (1993). Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. Trends Neurosci.
Pagina 184 - Tabara, H., Sarkissian, M., Kelly, WG, Fleenor, J., Grishok, A., Timmons, L., Fire, A. and Mello, CC (1999) The rde-1 gene, RNA interference and transposon silencing in C. elegans. Cell 99, 123-132.
Pagina 286 - Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Scholer, H., and Smith, A. (1998). Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391.
Pagina 345 - Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O., and Clevers, H. (1996) XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos.
Pagina 342 - Moon, R. T. (1997). Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway.
Pagina 347 - H., and Kemler, R. (1989) The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J.
Pagina 476 - Krauss, S., Concordet, JP, and Ingham, PW (1993). A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75, 1431-1444.