PharmacologyChurchill Livingstone, 1995 - 855 pagine Pharmacology is now firmly established as a world wide best-selling and highly acclaimed textbook for medical and science students. Its successful approach emphasies the mechanisms by which drugs act and relates these to the overall pharmacological effects and clinical uses. It sets out for the reader a clear route from a molecular understanding of receptors and drug actions, to the therapeutic uses of the most important groups of drugs. For the Fifth Edition the text has been completely updated, incorporating significant new information published in the last few years, while obsolete material has been removed. New agents are fully discussed as well as extensions of basic knowledge which presage further drug development. Book jacket. |
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Risultati 1-3 di 89
Pagina 71
... important factor . • Many drugs are weak acids or weak bases , whose state of ionization varies with pH according to the Henderson - Hasselbalch equation . • With weak acids or bases , only the uncharged species ( the protonated form ...
... important factor . • Many drugs are weak acids or weak bases , whose state of ionization varies with pH according to the Henderson - Hasselbalch equation . • With weak acids or bases , only the uncharged species ( the protonated form ...
Pagina 140
... important in relation to the inactivation of the drugs listed above . Genetic variants of BChE occur ( see Ch . 42 ) , and these partly account for the variability in the duration of action of these drugs . The very short duration of ...
... important in relation to the inactivation of the drugs listed above . Genetic variants of BChE occur ( see Ch . 42 ) , and these partly account for the variability in the duration of action of these drugs . The very short duration of ...
Pagina 180
... important in vascular disease . Nerve endings . 5 - HT stimulates nociceptive ( pain - mediating ) sensory nerve ... important in the brain , in relation to mood and behavior ( see Chs . 24 , 27 and 29 ) . The 5 - HTID subtype , which is ...
... important in vascular disease . Nerve endings . 5 - HT stimulates nociceptive ( pain - mediating ) sensory nerve ... important in the brain , in relation to mood and behavior ( see Chs . 24 , 27 and 29 ) . The 5 - HTID subtype , which is ...
Sommario
SECTION ONE 16 Hemostasis and Thrombosis | 331 |
The Respiratory System | 351 |
General Principles | 367 |
Copyright | |
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acetylcholine acid action activity agents agonists anesthetics animals antagonists appears associated binding block blood body brain Ca2+ calcium cardiac cause cells central changes channels Chapter chemical clinical compounds concentration decrease dependence depression disease dopamine dose drugs effects enzyme evidence example excreted factor function given glucose half-life heart hormone important increase inhibition inhibitors injection insulin interaction involved known less liver mainly measured mechanism mediators membrane metabolism molecules myocardial infarction nerve neurons norepinephrine normal occurs orally organs pain pathway patients peptide Pharmacol pharmacological phase plasma potential pressure prevent produce protein reactions receptors reduced regulation release renal response result role secretion selective shown similar smooth muscle specific stimulation structure studies substances synthesis Table terminals therapeutic therapy tion tissues toxicity transmission transmitter treat treatment tubocurarine types unwanted effects usually various vascular