Current Topics in Developmental BiologyGerald P. Schatten Elsevier, 4 gen 2003 - 211 pagine Together with other volumes in this series, Volume 53 presents thoughtful and forward-looking articles on developmental biology and developmental medicine. The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development. This volume in particular will be essential reading for anyone interested in stem cells, signaling, medical implications of developmental determinants, hematopoeisis, axis specification, and molecular genetics of development.
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Dall'interno del libro
Risultati 1-5 di 45
Pagina ix
... ventral, left-right, and anterior-posterior (or their equivalents in other systems) are absolutely crucial and molecular determinants, especially β-catenin, are vital. Together with other volumes in this Series, this volume provides a ...
... ventral, left-right, and anterior-posterior (or their equivalents in other systems) are absolutely crucial and molecular determinants, especially β-catenin, are vital. Together with other volumes in this Series, this volume provides a ...
Pagina 5
... ventral pattern. Similarly, in more posterior positions, the underlying midline notochord plays an equivalent role in presumptive midbrain, hindbrain, and spinal cord regions. Although initial ventral patterning signals originate ...
... ventral pattern. Similarly, in more posterior positions, the underlying midline notochord plays an equivalent role in presumptive midbrain, hindbrain, and spinal cord regions. Although initial ventral patterning signals originate ...
Pagina 6
... ventral cell fates along the length of the neural tube. Much of this work has focused on the spinal cord of the ... ventral half of the neural tube, each characterized by the expression of a distinct set of genes (Briscoe et al.,1999 ...
... ventral cell fates along the length of the neural tube. Much of this work has focused on the spinal cord of the ... ventral half of the neural tube, each characterized by the expression of a distinct set of genes (Briscoe et al.,1999 ...
Pagina 7
... ventral patterning in vivo (Briscoe et al., 2000; Ericson et al., 1996). Given that these experiments support a model in which Shh acts as a long-range morphogen specifying multiple ventral cell fates in the presumptive spinal cord, the ...
... ventral patterning in vivo (Briscoe et al., 2000; Ericson et al., 1996). Given that these experiments support a model in which Shh acts as a long-range morphogen specifying multiple ventral cell fates in the presumptive spinal cord, the ...
Pagina 8
... ventral neural progenitors (Sander et al., 2000). Importantly, because the concentration gradient of Shh is notexpected to alter inNkx6.1mutants, ventral cells now appear to activate Dbx2at a concentration threshold that normally ...
... ventral neural progenitors (Sander et al., 2000). Importantly, because the concentration gradient of Shh is notexpected to alter inNkx6.1mutants, ventral cells now appear to activate Dbx2at a concentration threshold that normally ...
Sommario
1 | |
Could the Chromatin Structure Be the Driving Force? | 115 |
Examining the Emergence of Hematopoietic Cells in the Vertebrate Embryo | 139 |
Gene Regulatory Networks Signaling Pathways and Cellular Interactions | 159 |
Index | 199 |
Contents of Previous Volumes | 207 |
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Current Topics in Developmental Biology, Volume 53 Gerald P. Schatten Anteprima non disponibile - 2002 |
Parole e frasi comuni
aboral ectoderm activity allele asymmetry ATFs axis Biol blastomeres blastula blastula stage BMP4 bone cell fate cell types chick chondrocytes chromosome cleavage compartment Development 124 developmental differentiation domain dorsal Drosophila early ectoderm ectopic embryos encoding endoderm epithelial epithelium floor plate follicle formation function gastrulation gene expression Genet genomic imprinting Gli1 Gli2 Gli3 growth hedgehog genes Hedgehog signaling hematopoietic cells homologs HSCs imprinted genes induce interactions left–right limb bud lineages mammalian maternal McMahon mechanism mesendoderm mesoderm methylation mice micromeres midline molecular monoallelic morphogenesis mouse mRNA mutant Nature London neural tube neurons normal notochord pancreatic pathway patterning phenotype PMCs polarity polydactyly posterior precursors progenitors proliferation protein Ptc1 receptor region regulation repression repressor role sclerotome segment Shh expression Shh mutants Shh signaling somites Sonic hedgehog specification stem cells syndrome target tissues transcription factor upregulation vegetal ventral vertebrate Xenopus yolk sac zebrafish Zhang
Brani popolari
Pagina 158 - Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc. Natl. Acad. Sci. USA 93, 3444_3449.
Pagina 93 - AE (1996) Mutations of the human homolog of drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85, 841-851.
Pagina 96 - K. (1986). Fetal gut mesenchyme induces differentiation of cultured intestinal endodermal and crypt cells. Dev. Biol.
Pagina 90 - Ericson, J., Morton, S., Kawakami, A., Roelink, H., and Jessell, TM (1996). Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell 87, 661-673.
Pagina 112 - Wechsler-Reya, RJ, and Scott, MP (1999) Control of neuronal precursor proliferation in the cerebellum by Sonic hedgehog.
Pagina 106 - C. (1995). Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 121, 3163-3174.
Pagina 85 - McMahon, AP (1995). Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol.
Pagina 97 - Krauss, S., Concordet, JP, and Ingham, PW (1993). A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75, 1431-1444.