Recombinant DNA Research, Volume 3U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, 1976 Documents relating to "NIH guidelines for research involving recombinant DNA molecules," Feb. 1975/June 1976- . |
Altre edizioni - Visualizza tutto
Parole e frasi comuni
1976 Guidelines adenovirus animal Appendix approval assessment bacteria bacteriophage bacterium Bethesda binant DNA biological containment biological safety cabinets biosafety certification Class cloning containment levels Director discussion disease DNA Molecule Program DNA segments DNA sequences EK2 host-vector environment Environmental Impact Escherichia coli eukaryotic Exempt FEDERAL REGISTER foreign DNA FREDRICKSON genes genetic genome hazard Helinski host-vector systems HUTT infection inserted Institutes of Health JULY 28 laboratory meeting ment Molecule Program Advisory mRNA National Institutes NIH Guidelines ORDA organisms P4 facility pathogenic phage physical containment plant pathogens plasmid polyoma potential PRG-NIH PRG-RAC procedures Program Advisory Committee prokaryotes proposed revised Guidelines question recom Recombinant DNA Activities recombinant DNA experiments recombinant DNA molecules recombinant DNA research recommended responsibility risk risk-assessment scientific shotgun experiments Sinsheimer specific strains tainment tion Tooze vector viral DNA virus viruses Workshop
Brani popolari
Pagina 86 - Hearings before the Subcommittee on Science, Technology, and Space of the Senate Committee on Commerce, Science, and Transportation, 95th Cong, 1st Sess (1977); Hearings on HR 4759 et al.
Pagina 12 - ... the Environmental Protection Agency [EPA] and the Occupational Safety and Health Administration [OSHA]).
Pagina 67 - Determined, for the sake of all mankind, to exclude completely the possibility of bacteriological (biological) agents and toxins being used as weapons...
Pagina 32 - Contaminated materials that are to be decontaminated at a site away from the work area...
Pagina 30 - Applicability. The Guidelines are applicable to all recombinant DNA research within the United States or its territories which is conducted at or sponsored by an Institution that receives any support for recombinant DNA research from NIH.
Pagina 49 - Transfer of a drug resistance trait to microorganisms that are not known to acquire it naturally if such acquisition could compromise the use of a drug to control disease agents in human or veterinary medicine or agriculture.
Pagina 219 - DNA molecules are defined as either (i) molecules which are constructed outside living cells by joining natural or synthetic DNA segments to DNA molecules that can replicate in a living cell, or (ii) DNA molecules that result from the replication of those described in (i) above.
Pagina 175 - HEPA filtered mass recirculated air flow for product protection. The cabinet exhaust air is filtered through a HEPA filter. The face velocity of the inward flow of air through the full-width open front is 75 feet per minute or greater. Design and performance specifications...
Pagina 167 - ... many years. Considerable information therefore already exists for the design of physical containment facilities and the selection of laboratory procedures applicable to organisms carrying recombinant DNAs. 1619] The existing programs rely upon mechanisms that, for convenience, can be divided into two categories: (1) A set of standard practices that are generally used in microbiological laboratories...
Pagina 49 - EL Sheldon, and O. Smithies (1977). Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning.