PharmacologyAdapted for the U.S., this New Edition of PHARMACOLOGY, a popular UK text, describes what drugs do and emphasizes the mechanisms by which they act. The U.S. edition is revised and updated to reflect the substantial differences in drug names, FDA approvals, terminology, and guidelines for use. It also boasts new and revised chapters to ensure that students are up to date on the very latest information. Each chapter begins with a summary of information essential to the chapter and key points are highlighted within the text to alert students to crucial concepts. Spanish version also available, ISBN: 84-8174-492-1 |
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Pagina 78
Excretion involves the loss of chemically unchanged drug, metabolism the
conversion of one chemical entity to another. The main routes by which drugs
and their metabolites leave the body are: • the kidneys • the hepato-biliary system
• the ...
Excretion involves the loss of chemically unchanged drug, metabolism the
conversion of one chemical entity to another. The main routes by which drugs
and their metabolites leave the body are: • the kidneys • the hepato-biliary system
• the ...
Pagina 86
5.5 The effect of urinary pH on drug excretion. ... Table 5.5 Drugs that are
excreted largely unchanged in the urine 100-75% Amiloride, furosemide,
chlorothiazide, ... BILIARY EXCRETION AND ENTEROHEPATIC CIRCULATION
Liver cells ...
5.5 The effect of urinary pH on drug excretion. ... Table 5.5 Drugs that are
excreted largely unchanged in the urine 100-75% Amiloride, furosemide,
chlorothiazide, ... BILIARY EXCRETION AND ENTEROHEPATIC CIRCULATION
Liver cells ...
Pagina 351
Filtered/day Excreted/day' % reabsorbed Na*(mEq) 25000 150 99+ K*(mEq) 600
90 93+ Cr-(mEq) 18000 150 99+ HC03- ... of the internal milieu, so on a low-
sodium diet (for instance) NaCI excretion may be reduced to as low as 20 mmol/
day.
Filtered/day Excreted/day' % reabsorbed Na*(mEq) 25000 150 99+ K*(mEq) 600
90 93+ Cr-(mEq) 18000 150 99+ HC03- ... of the internal milieu, so on a low-
sodium diet (for instance) NaCI excretion may be reduced to as low as 20 mmol/
day.
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Sommario
general principles | 2 |
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
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absorption acetylcholine acid action activity agents agonists anesthetic antagonists associated binding block blood body brain calcium cardiac cause cells changes channels Chapter chemical clinical complex compounds concentration decrease discussed disease dopamine dose drugs effects enzyme evidence example excretion factor function gene given glucose half-life heart hormone humans important increase inhibition inhibitors injection insulin interaction intracellular involved known less liver mainly mechanism mediators membrane metabolism molecules muscarinic myocardial infarction nerve terminals neurons norepinephrine normal occurs orally oxide pain particularly pathway patients peptide pharmacological phase plasma potential pressure prevent produce protein reactions receptors reduced regulation release renal response result role secretion selective shown similar smooth muscle specific stimulation structure studies substance sympathetic synthesis Table therapeutic therapy tissues transmission transmitter transport treat treatment tubocurarine unwanted effects uptake various vascular
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Informazioni bibliografiche
| Titolo | Pharmacology |
| Autore | H. P. Rang |
| Edizione | 4, illustrata |
| Editore | Churchill Livingstone, 2001 |
| Provenienza dell'originale | la University of Michigan |
| Digitalizzato | 18 ago 2008 |
| ISBN | 0443065748, 9780443065743 |
| Lunghezza | 839 pagine |
| Esporta citazione | BiBTeX EndNote RefMan |