PharmacologyChurchill Livingstone, 2001 - 839 pagine Adapted for the U.S., this New Edition of PHARMACOLOGY, a popular UK text, describes what drugs do and emphasizes the mechanisms by which they act. The U.S. edition is revised and updated to reflect the substantial differences in drug names, FDA approvals, terminology, and guidelines for use. It also boasts new and revised chapters to ensure that students are up to date on the very latest information. Each chapter begins with a summary of information essential to the chapter and key points are highlighted within the text to alert students to crucial concepts. Spanish version also available, ISBN: 84-8174-492-1 |
Dall'interno del libro
Risultati 1-3 di 75
Pagina 78
... metabolism 83 Pharmacologically active drug metabolites 83 Renal excretion of drugs and drug metabolites 84 Glomerular filtration 84 Tubular excretion and reabsorption 84 Diffusion across the renal tubule 85 Drug elimination expressed ...
... metabolism 83 Pharmacologically active drug metabolites 83 Renal excretion of drugs and drug metabolites 84 Glomerular filtration 84 Tubular excretion and reabsorption 84 Diffusion across the renal tubule 85 Drug elimination expressed ...
Pagina 84
... metabolites may have pharmacological actions similar to the parent compound ( e.g. benzodiazepines , many of which form long - lived active metabolites that cause their effects to persist after the parent drug has disappeared ) . There ...
... metabolites may have pharmacological actions similar to the parent compound ( e.g. benzodiazepines , many of which form long - lived active metabolites that cause their effects to persist after the parent drug has disappeared ) . There ...
Pagina 764
... metabolism . Toxic metabolites can form covalent bonds with target molecules , or alter the target molecule by non - covalent interactions ( Table 49.2 ) . Some metabolites do both . The liver is of paramount importance in drug metabolism ...
... metabolism . Toxic metabolites can form covalent bonds with target molecules , or alter the target molecule by non - covalent interactions ( Table 49.2 ) . Some metabolites do both . The liver is of paramount importance in drug metabolism ...
Sommario
general principles | 11 |
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
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5-HT receptors absorption acetylcholine action potential activity adrenoceptors agents agonists amino acids anesthetics antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ cancer cardiac cause cells chemical cholinergic clinical compounds cytokines decrease depolarization depression disease diuretics dopamine dose drugs enzyme estrogens ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals neurons nicotine norepinephrine normal occurs opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma concentration platelet presynaptic produce prostaglandins protein reactions receptor antagonists reduced release renal response result role secretion side-effects smooth muscle sodium stimulation substance sympathetic synaptic synthesis therapeutic therapy tissue toxicity transmission transmitter treatment tubule unwanted effects uptake vascular vasoconstriction vitamin