PharmacologyChurchill Livingstone, 2001 - 839 pagine Adapted for the U.S., this New Edition of PHARMACOLOGY, a popular UK text, describes what drugs do and emphasizes the mechanisms by which they act. The U.S. edition is revised and updated to reflect the substantial differences in drug names, FDA approvals, terminology, and guidelines for use. It also boasts new and revised chapters to ensure that students are up to date on the very latest information. Each chapter begins with a summary of information essential to the chapter and key points are highlighted within the text to alert students to crucial concepts. Spanish version also available, ISBN: 84-8174-492-1 |
Dall'interno del libro
Risultati 1-3 di 80
Pagina 57
... TOXICITY Before any new compound is approved for testing in humans , extensive toxicity testing is done in various animal species and with in vitro systems . The crudest type of toxicity test is the LD50 ( lethal dose for 50 % of a ...
... TOXICITY Before any new compound is approved for testing in humans , extensive toxicity testing is done in various animal species and with in vitro systems . The crudest type of toxicity test is the LD50 ( lethal dose for 50 % of a ...
Pagina 58
... toxicity when used under clinical conditions . As Witts has pointed out , however : " The final test of the safety of a drug is in fact its release for general use . " The only way that rare but serious toxicities can be detected is by ...
... toxicity when used under clinical conditions . As Witts has pointed out , however : " The final test of the safety of a drug is in fact its release for general use . " The only way that rare but serious toxicities can be detected is by ...
Pagina 764
... toxicity by the animal studies . * Safety of a drug ( as opposed to toxicity ) can only be established during use in humans . Types of drug toxicity Toxic effects of drugs can be : - related to the principal pharmacological action ...
... toxicity by the animal studies . * Safety of a drug ( as opposed to toxicity ) can only be established during use in humans . Types of drug toxicity Toxic effects of drugs can be : - related to the principal pharmacological action ...
Sommario
general principles | 11 |
molecular aspects | 19 |
Method and measurement in pharmacology | 47 |
Copyright | |
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5-HT receptors absorption acetylcholine action potential activity adrenoceptors agents agonists amino acids anesthetics antidepressant antipsychotic asthma benzodiazepines binding block blood bradykinin brain Ca2+ cancer cardiac cause cells chemical cholinergic clinical compounds cytokines decrease depolarization depression disease diuretics dopamine dose drugs enzyme estrogens ethanol excretion factors function GABA gastrointestinal gene glucocorticoids glucose glutamate histamine hormone important inactivation increase inflammatory inhibition inhibitors injection insulin interaction intracellular intravenous kinase leptin liver mainly mechanism of action mediators membrane metabolism metabolites molecular molecules morphine muscarinic nerve terminals neurons nicotine norepinephrine normal occurs opioid orally oxide pathway patients peptide peripheral Pharmacokinetic Pharmacol pharmacological physiological pituitary plasma concentration platelet presynaptic produce prostaglandins protein reactions receptor antagonists reduced release renal response result role secretion side-effects smooth muscle sodium stimulation substance sympathetic synaptic synthesis therapeutic therapy tissue toxicity transmission transmitter treatment tubule unwanted effects uptake vascular vasoconstriction vitamin