Signaling Through Cell Adhesion Molecules

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CRC Press, 30 apr 2019 - 424 pagine
The field of signal transduction research is one of the fastest growing in all of biomedical research in recent years. Signaling through cell adhesion molecules have long been of interest because of their importance in embryonic development, homeostasis, immune responses, wound healing , and malignant transformation. However, it is only recently re

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Sommario

The Use of Chimeric Receptors in the Study of Integrin Signaling
3
Using Synthetic Peptides to Mimic Integrins Probing Cytoskeletal Interactions and Signaling Pathways
19
Use of the Yeast TwoHybrid System for the Characterization of Integrin Signal Transduction Pathways Identification of the IntegrinLinked Kinase p...
33
Focal Adhesion Kinase and its Associated Proteins
49
Analysis of Paxillin as a MultiDomain Scaffolding Protein
63
p130Cas jn integrin Signaling
81
Specificity of Integrin Signaling
101
Late Events and Biological Functions of Integrin Signaling
115
Integrin Signaling in Pericellular Matrix Assembly
183
InsideOut Signaling by Integrins
201
Studies of Integrin Signaling Through Platelet 𝛂11b𝛃3
203
Tracking Integrin Mediated Adhesion Using Green Fluorescent Protein and Flow Cytometry
217
Expression Cloning of Proteins That Modify Integrin Activation
235
Regulation of Cell Contractility by RhoA Stress Fiber and Focal Adhesion Assembly
245
General Methods for Signaling Studies of Cell Adhesion Molecules
261
Intra and Intercellular Localization of Proteins in Tissue in situ
263

Methods for Study of Integrin Regulation of MAP Kinase Cascades
117
Methods for Analysis of AdhesionDependent Cell Cycle Progression
129
Integrin Modulation of Mitogenic Pathways Involved in Muscle Differentiation
141
Methods for Studying Anoikis
161
Functional Analysis of FAK and Associated Molecules in Cell Migration
167
Optical Microscopy Studies of Ca2+ i Signaling
279
Wnt Signaling in Xenopus Embryos
303
Index
357
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