PharmacologyChurchill Livingstone, 1991 - 955 pagine Describes the mechanisms by which drugs act and relating these to their overall pharmacological effects and clinical uses. This new edition emphasizes the chemical structures of those drugs for which knowledge of structure-activity relationships enhances appreciation of how the drugs act. |
Sommario
general principles | 3 |
molecular aspects | 24 |
Measurement in pharmacology | 49 |
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acetylcholine acid action activity agents agonists anaesthetic antagonists appears associated binding block blood body brain calcium cardiac cause cells central changes channels Chapter chemical clinical compounds concentration decrease depends depression disease dopamine dose drugs effects enzyme evidence example excretion factor function given glucose half-life heart histamine hormone important increase inhibition inhibitors injection insulin interaction involved known less liver mainly measured mechanism mediators membrane metabolites molecules myocardial infarction nerve neurons noradrenaline normal occur orally organisms pain particularly pathway patients peptide pharmacological phase plasma platelet potential pressure prevent probably produce protein reactions receptors reduced regulation release resistance response result secretion selective shown similar smooth muscle sodium specific stimulation structure studies substances sympathetic synthesis Table term terminals therapeutic tissues toxic transmission transmitter treat treatment tubocurarine types Unwanted effects usually various