Comprehensive Treatise of Electrochemistry: Volume 10 Bioelectrochemistry

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Peter Horsman, Brian E. Conway, E. Yeager
Springer Science & Business Media, 28 feb 1985 - 564 pagine
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1.1. Definition of Terms-Thrombosis, Thromboembolic Disease, Atherosclerosis, and Blood Clotting The terms heart attack or myocardial infarction are more commonly used than thrombosis. The infarct-muscle destruction is simply the end result and thrombosis is the real cause of the heart attack. Thrombosis may be defined as the process of formation of a coalescent or agglutinated solid mass of blood components in the blood stream. Thrombi formed in either arteries or veins often cause occlusion in the vascular system and prevent blood flow. Obstruc to the blood vessel usually occurs at the site where the thrombi deposit. tion Furthermore, thrombi may break loose, travel through the circulating blood stream, and cause obstruction at some distal point of narrowing elsewhere. The mass or thrombus that moves is referred to as an "embolus." The two phenomena are lumped together under the term thromboembolic disease. Thrombosis that reduces blood supply to the heart is the primary factor in heart attacks.
 

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Indice

The Origin of Electrical Potential in Biological Systems
1
1 Electrical Potential of Biomolecules
2
2 Electrical Potential at Biomolecular Interfaces
39
3 Transmembrane Potential across Cell Membranes
65
4 Molecular Interaction in Biological Systems
109
Electrochemistry of Low Molecular Weight Organic Compounds of Biological Interest
131
2 Catecholamines
132
3 Phenothiazines
145
3 Thermodynamic Studies of Biological Molecules
306
4 Kinetics and Mechanisms of Biological Electron Transfer Reactions
313
5 Conclusions
340
References
341
Electrochemical Aspects of Metabolism
347
2 The Living Cell as an Electrochemical System
348
3 Electrochemical Regulation of Metabolism
356
4 Electrochemical Processes and Disease
370

4 aTocopharol and aTocopherylquinone
159
5 Purines
170
6 Conclusions
184
References
185
Electrochemistry of Biopolymers
189
2 Proteins
190
3 Polysaccharides
200
4 Nucleic Acids
203
5 Nucleoproteins
219
6 Outlook
225
References
226
Bioelectrocatalysis
231
2 Physicochemical Properties of Enzymes
233
3 Methods of Immobilization of Enzymes
246
4 Electrochemical Properties of Protein Macromolocules and Their Active Groups
250
5 Methods of Conjugation of Electrochemical and Enzymic Reactions
259
6 The Use of Enzymes to Accelerate Electrochemical Reactions
261
7 Mechanism of Bioelectrocatalysis
283
8 Prospects for Practical Utilization of Bioelectrocatalysis
287
References
291
Electrochemical Aspects of Bioenergetics
297
2 Interfacial Properties of Electrodes and Biological Membranes
299
References
376
Electrochemistry of the Nervous Impulse
381
2 Electrochemical Models of the Nerve Fiber
387
3 Excitation Propagation
394
4 Ionic Transport across Membranes
408
5 Channels in Biomembranes
422
6 Conclusions
440
References
441
An Electrochemical Approach for the Solution of Cardiovascular Problems
445
1 Introduction
446
2 Hematological and Electrochemical Aspects of Blood Coagulation Mechanisms
448
3 An Electrokinetic Approach for the Characterization of Blood Vessel Walls and of Blood Cells and for the Selection of Anticoagulant Drugs
464
4 An Electrochemical Approach for the Selection of Vascular and Heart Valve Prostheses
476
5 Conclusions
486
References
487
Electrochemical Techniques in the Biological Sciences
491
1 Electroanalytical Techniques
492
2 Electrophysiology
514
3 Electrobiology
520
References
528
Index
531
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