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Pagina 114
Table 1 Data on subject material at the beginning of the observation period No of
Age Sex Body weight Fasting blood k - value of subjects years in % of ideal
glucose conc . IGTT weight mg % I . High insulin responders 26 + 1 . 2 40 F 97 £
1 .
Table 1 Data on subject material at the beginning of the observation period No of
Age Sex Body weight Fasting blood k - value of subjects years in % of ideal
glucose conc . IGTT weight mg % I . High insulin responders 26 + 1 . 2 40 F 97 £
1 .
Pagina 123
30 90 180 Table 2 Blood glucose and plasma insulin levels ( mean I S . E . M . )
in schistosomatic patients after oral glucose load and TV tolbutamide glucose ,
glucagon and insulin Stimulus Minutes - - Areas - 60 120 0 - 60 min 0 - 180 min .
30 90 180 Table 2 Blood glucose and plasma insulin levels ( mean I S . E . M . )
in schistosomatic patients after oral glucose load and TV tolbutamide glucose ,
glucagon and insulin Stimulus Minutes - - Areas - 60 120 0 - 60 min 0 - 180 min .
Pagina 127
HSS - In . 3 ) LHSS - Tin - 5 - - I NC ( : 51 5 ) BLOOD GLUCOSE ( mg / 100 mi )
PLASMA INSULIN ( U / ml ) MSS . Iin . 2 ) MSS . Tino51s NCIS ) 0 10 20 30 45
120 min 10 30 45 60 SO 120 min Fig . 5 Glucagon tolerance test . Blood glucose
and ...
HSS - In . 3 ) LHSS - Tin - 5 - - I NC ( : 51 5 ) BLOOD GLUCOSE ( mg / 100 mi )
PLASMA INSULIN ( U / ml ) MSS . Iin . 2 ) MSS . Tino51s NCIS ) 0 10 20 30 45
120 min 10 30 45 60 SO 120 min Fig . 5 Glucagon tolerance test . Blood glucose
and ...
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ACTH activity added amounts antibody antigen antiserum assay basal Berson binding biological blood bound bovine buffer C-peptide chromatography Clin compared concentration containing cyclic AMP decreased demonstrated determined developed diabetes dilution dose effect Endocr Endocrinology enzymes experiments extract fraction glucagon glucose glucose tolerance growth hormone higher human increase incubation indicated inhibition injection insulin insulin response islets isolated Italy labelled levels LH-RH LHRH liver cells lower material mean measured membranes method minutes normal observed obtained oral pancreas patients peak performed period phase pituitary plasma porcine pork possible preparations present proinsulin protein rabbit radioactivity radioimmunoassay release reported response samples secretion separation serum showed shown significant similar specific stimulation subjects subunit suggest synovial fluid Table tion treatment trypsin tubes University values weight Yalow