Biochemistry for the Medical SciencesWiley, 1983 - 952 pagine This outstanding text, written in a clear, concise and easy-to-read style, provides students with an in-depth explanation of how each metabolic pathway is directly related to physiology, pharmacology, and clinical medicine. Emphasis is given to those medical problems encountered most frequently in daily clinical practice. Basic metabolism is presented as a coherent part of physiology and reference is made to the matabaolic aberrations seen in clinical situations. |
Sommario
Kinetic factors and the metabolic role of | 3 |
Thermodynamics in metabolism | 10 |
Kinetics and metabolism | 46 |
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2-oxoglutarate absorption acetyl-CoA acyl-CoA adipose tissue aerobic AGº allosteric amino acids anaerobic glycolysis bile blood bloodstream carbohydrate carbon atoms carnitine carriers catalysed cell CH2COO CH₂OH CH₂OPO Chapter cholesterol chylomicrons citrate coenzyme complex compounds converted cytochrome cytosol discussed electron transfer chain enzyme enzyme activity equilibrium example fatty acid oxidation fibres Figure flux flux-generating step formation fructose fuel glucose 6-phosphate glycerol glycogen glycolytic H₂O haemoglobin heart heat hexokinase hydrogen hydrolysis important increase inhibition inhibitor inner mitochondrial membrane intermediate intestine involved ketone bodies kinase kinetics known lactate lipase lipid lipoprotein lipoprotein lipase liver mechanism metabolic pathway mitochondria molecules muscle NAD+ NADH near-equilibrium Newsholme non-equilibrium reaction normal nucleotides occur oxaloacetate oxidative phosphorylation oxoglutarate dehydrogenase oxygen patients phosphate physiological production protein proton pyruvate ratio reduced regulation role Section structure succinate succinyl-CoA synthesis Table TCA cycle temperature thermodynamic transport triacylglycerol utilization vivo Vmax